Description
Syn-Coll (Palmitoyl Tripeptide-5) – 200mg
Target the root cause of aging skin: collagen loss. This isn’t a moisturizer. It’s a direct tool for researchers focusing on skin regeneration. Syn-Coll, or Palmitoyl Tripeptide-5, is a synthetic peptide built to mimic your skin’s natural Thrombospondin-1 (TSP-1) protein. Its primary studied function? To significantly upregulate TGF-β, the key growth factor that tells fibroblasts to produce Type I and III collagen.
Think of collagen as the structural framing of a house. Over time, UV exposure and natural aging break it down while also ramping up enzymes (MMP-1, MMP-3) that further degrade it. Your skin sags and wrinkles. The research on Syn-Coll points to a two-pronged defense: boost new collagen synthesis and inhibit the enzymes that destroy it. Published data suggests it can stimulate collagen production 2-3 times over baseline and may suppress collagen breakdown by up to 119%. In comparative lab studies, it’s been shown to be about 3.5 times more impactful in reducing wrinkle depth than control compounds and potentially 60% more powerful than Palmitoyl Pentapeptide-4.
We stock it because the mechanism is solid. It’s palmitoylated for better stability and bioavailability in experimental models. Beyond collagen, studies indicate it may support skin barrier function, helping to retain moisture, and even show potential in influencing melanin production pathways when combined with specific derivatives.
This is a precision research chemical. You’re getting 200mg of high-purity Syn-Coll for your in-vitro studies. The specs are clean, and the research is cited below. If your work involves dermatology, cosmetic science, or cellular repair mechanisms, this is a primary compound you need on the bench.
Specifications:
- Purity: >98%
- Sequence: Palmitoyl-Lys-Val-Lys
- Molecular Formula: C33H65N5O5
- Molecular Weight: 611.9 g/mol
- Other Names: Palmitoyl Tripeptide-5, Tripeptide-5
- PubChem CID: 11950477
Research References: The claims and data presented are derived from the published scientific literature (e.g., Varga et al., Biochem J. 1987; Murphy-Ullrich et al., Cytokine Growth Factor Rev. 2000; Kim et al., Arch Dermatol Res. 2017; Gorouhi & Maibach, Int J Cosmet Sci. 2009). This product is for laboratory research use only in controlled settings. It is NOT for human or animal consumption, nor is it a drug, cosmetic, or dietary supplement. Handle with appropriate PPE and procedures. By purchasing, you confirm you are a qualified researcher operating in a licensed facility and understand these terms.
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