MOTS-c Peptide (10mg) – Research Grade

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This is MOTS-c. Think of it as a direct signal from your cell’s power plants. It’s a 16-amino acid mitochondrial-derived peptide (MDP), and the research coming out on it is serious. We’re talking about a compound that appears to regulate fundamental energy processes at the cellular level. This isn’t magic; it’s hardcore biochemistry, and for the right lab, it’s a powerful tool.

The early data is compelling. Studies suggest MOTS-c operates systemically, influencing how the body manages fuel. It appears to activate the AMPK pathway—a central regulator of cellular energy. In models, this has been linked to supporting healthy metabolic function, promoting the utilization of glucose and fatty acids for energy, and influencing muscle cell responsiveness.

Here’s the breakdown of key research areas:

• Metabolic & Weight Regulation: Research indicates MOTS-c may help regulate fat metabolism. It appears to promote brown adipose tissue and support healthy lipid oxidation, potentially countering metabolic dysfunction linked to insulin resistance.
• Muscle Function: It targets skeletal muscle. Studies suggest it can enhance cellular glucose uptake through an insulin-independent pathway, which may support muscle function and combat age-related metabolic decline.
• Bone Density: Evidence points to MOTS-c promoting type I collagen synthesis in osteoblasts via the TGF-β/SMAD pathway. This suggests a potential role in supporting bone strength and integrity.
• Physical Performance: Murine studies show improved endurance and motor coordination following MOTS-c introduction, independent of weight changes, pointing to direct optimization of cellular energy metabolism.
• Cellular Longevity: As a mitochondrial signal, MOTS-c is implicated in influencing pathways related to cellular aging, including NAD+ metabolism and stress resistance, potentially supporting overall cellular healthspan.

Specifications:

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
• Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
• Molecular Weight: 2174.64 g/mol
• Purity: >98% (HPLC verified)
• Synonyms: 12S rRNA-c, MT-RNR1

This is a research-grade peptide. It is supplied as a sterile, lyophilized powder in a 10mg vial. Proper laboratory handling protocols are required. The data referenced is from published, peer-reviewed studies (see citations in source material).