Lipopeptide (Biopeptide EL) – 200mg

SKU: Palmitoyl Hexapeptide-12 | Oligopeptide-34

You’re looking at Lipopeptide, also known in the lab as Biopeptide EL or Palmitoyl Hexapeptide-12. This isn’t a flashy cosmetic ingredient; it’s a precision research tool built around a specific six-amino acid chain (VGVAPG) attached to a palmitic acid group. That fatty acid tail isn’t for show—it’s believed to help the peptide penetrate deeper into cellular structures for targeted study.

The core action is based on its design: it mimics a fragment of the body’s own elastin protein. In research models, this mimicry allows it to interact directly with fibroblast cells. Fibroblasts are the workhorses that build and maintain the structural support system of skin—the extracellular matrix (ECM). The ECM is where you find the critical proteins: collagen for strength, elastin for snap-back, and hyaluronic acid for hydration.

Here’s what the published literature suggests researchers are investigating with this compound:

• Fibroblast Activity & ECM Support: Studies indicate the VGVAPG sequence may stimulate fibroblast proliferation and influence the cells’ production of key ECM components, notably collagen and hyaluronic acid. It’s also been observed to act as a chemoattractant, potentially guiding fibroblasts to target areas.
• Pigmentation Pathways: In vitro research points to a potential modulatory effect on melanocytes, the cells responsible for melanin. Data suggests Lipopeptide may downregulate key genes and enzymes in the melanogenesis pathway, leading to observed reductions in melanin content in experimental models.
• Inflammatory Response Modulation: Scientific inquiry explores Lipopeptide’s potential influence on pro-inflammatory cytokines like IL-6 in skin cells. By possibly regulating these signals, the peptide may help study mechanisms related to ECM preservation and the activity of matrix-degrading enzymes (MMPs).

Specifications:

• Sequence: Pal-Val-Gly-Val-Ala-Pro-Gly-OH
• Molecular Formula: C38H68N6O8
• Molecular Weight: 736.98 g/mol
• Purity: >98% (HPLC verified)
• Format: Lyophilized (freeze-dried) powder
• Quantity: 200mg in sterile glass vial

Important Notice:

The product presented here is a research chemical. It is supplied as a lyophilized powder strictly for in-vitro laboratory experimentation and analysis by qualified, licensed professionals. It is NOT intended for human or animal consumption, diagnostic use, or therapeutic application. All information provided is for educational and research reference purposes only. By purchasing, you acknowledge and certify that you are authorized to handle such materials for scientific research in accordance with all applicable laws and institutional guidelines.

References (Cited in Description):

1. Tajima, S., et al. (1997). Arch Dermatol Res.
2. Senior, R.M., et al